Professor, Institute of Brain Functional Genomics, East China Normal University
Email: dmyin@brain.ecnu.edu.cn
Phone: 86-21-62232016
Office: 3663 Zhongshan Road N., Shanghai, 200062, China
Neural plasticity; Neuroprotection; Schizophrenia; Stroke
Yin lab focuses on the mechanistic and translational study of neural plasticity and neuroprotection. Neural plasticity refers to the adaptive changes of the structure and function of the nervous system with the changes of internal and external environment. Neural plasticity can occur at the synaptic and cellular levels, including changes in synaptic transmission and changes in nerve cell excitability. Neural plasticity is a necessary condition for normal physiological function of the body, and the abnormal neuroplasticity is closely related to the occurrence of schizophrenia and other mental diseases.
2008 Ph. D., Neuroscience Research Institute, Peking University, Beijing, China
2003 M. D., Nanjing Medical University, Nanjing, China
2014-present Professor, Institute of Brain Functional Genomics, East China Normal University
2013-2014 Assistant Research Scientist, Department of Neuroscience and Regenerative Medicine, Georgia Regents University
2008-2013 Postdoctoral Fellow, Institute of molecular medicine and genetics, Georgia Regents University
2015 Eastern Scholar at Shanghai Institutions of Higher Learning
2015 Shanghai Rising-Star in Science and Technology
2012 NASADR Young Investigator Award, Brain & Behavior Research Foundation
2010 Outstanding Thesis Award (Ph. D. thesis), Peking University
2009 Best Students Award, the Society for Neuroscience, China, 2009
- Zhou HQ, Zhuang LJ, Bao H, Li S, Dai FY, Wang P, Li Q*, Yin DM*. Olfactory regulation by dopamine and DRD2 receptor in the nose. Proc Natl Acad Sci U S A. 119(11):e2118570119, 2022.
- Zhang YQ, Lin WP, Huang LP, Zhao B, Zhang CC, Yin DM*. Dopamine D2 receptor regulates cortical synaptic pruning in rodents. Nat Commun. 12(11):6444, 2021.
- Wang YY, Zhao B, Wu MM, Zheng LX, Lin L, Yin DM*. Overexpression of neuregulin 1 in GABAergic interneurons results in reversible cortical disinhibition. Nat Commun. 12(1):278, 2021.
- Zhang HL, Han W, Du YQ, Zhao B, Yang P, Yin DM*. SRC3 Acetylates Calmodulin in the Mouse Brain to Regulate Synaptic Plasticity and Fear Learning. J Biol Chem. 297(3):101044, 2021.
- Zhang HL, Zhao B, Han W, Sun YB, Yang P, Chen Y, Ni D, Zhang J, Yin DM*. Acetylation of Calmodulin Regulates Synaptic Plasticity and Fear Learning. J Biol Chem. 297(3):101034, 2021.
- Yin DM#, Chen YJ#, Liu S, Jiao H, Shen C, Sathyamurthy A, Lin TW, Xiong WC, Li BM, Mei L*, Bergson C*. Calcyon Stimulates Neuregulin 1 Maturation and Signaling. Mol Psychiatry 20: 1251-60, 2015.
- Yin DM, Sun XD, Bean JC, Lin TW, Sathyamurthy A, Xiong WC, Gao TM, Chen YJ*, Mei L*. Regulation of spine formation by ErbB4 in PV-positive interneurons. J Neurosci. 33:19295-303, 2013.
- Yin DM#, Chen YJ#, Lu YS, Bean JC, Sathyamurthy A, Shen C, Liu X, Lin TW, Smith AC, Xiong WC, Mei L*. Reversal of behavioral deficits and synaptic dysfunction in mice overexpressing neuregulin 1. Neuron 78:644-657, 2013.