Associate Professor, Institute of Cognitive Neuroscience, School of Psychology and Cognitive Science, East China Normal University
Email: czhuang@psy.ecnu.edu.cn
Office: Room 315 Old Library Building, 3663 North Zhongshan Road, Shanghai
Magnetic Resonance Imaging, Normal Brain Aging, White Matter Hyperintensities, Brain Connectome, Neurodegenerative Disease
Chu-Chung Huang’s research focuses on depicting brain structural and functional aging trajectories using non-invasive magnetic resonance imaging techniques. Given that the brain structure is fundamental to cognitive function, it is important to understand the interaction between gray matter, as the information processing units, and white matter, as the signal pathways. A deeper understanding of brain structural connectome might provide insight into cognition, as well as the development of neurodegenerative diseases and mental illness. Therefore, Dr. Huang’s primary research goal is to integrate the most advanced neuroimaging methods, including cortical morphometry, diffusion MRI, and quantitative imaging techniques, to reconstruct the human brain networks and related metrics as the probe for brain performance, with the aim of providing objective biomarker for brain health status evaluation at different stages of human lifespan.
2014 Ph.D. of Biomedical Imaging and Radiological Sciences, Department of Biomedical Imaging and Radiological Sciences, Yang-Ming University
2013 Visiting Student, Brain Mapping Unit, Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom
2009 Bachelor of Biomedical Imaging and Radiological Sciences, Department of Biomedical Imaging and Radiological Sciences, Yang-Ming University
2021-Present Associate Director, Children’s Brain Imaging Center, East China Normal University, Shanghai, China
2020-Present Associate Professor, School of Psychology and Cognitive Science, East China Normal University, Shanghai, China
2019-2020 Postdoctoral Researcher, Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China
2019 Visiting Scholar, Cardiff University’s Brain Research Imaging Centre (CUBRIC), Cardiff University, Cardiff, United Kingdom
2018-2019 Assistant Researcher, Aging and Health Research Center, Yang- Ming University
2014-2018 Postdoctoral Researcher, Brain Connectivity Lab, Institute of Neuroscience, Yang Ming University
- Huang CC, Chou KH, Lee WJ, Yang AC, Tsai SJ, Chen LK, Chung CP, Lin CP. Brain white matter hyperintensities-predicted age reflects neurovascular health in middle-to-old aged subjects. Age & Ageing. 2022 May 1;51(5):afac106. doi: 10.1093/ageing/afac106.
- Hsu CCH, Chong ST, Kung YC, Kuo KT, Huang CC*, Lin CP*. Integrated Diffusion Image Operator (iDIO): A tool for automated configuration and processing of diffusion MRI data. bioRxiv. 2022.03.14. 483870; doi: 10.1101/2022.03.14.483870.
- Huang CC, Rolls ET, Hsu CH, Feng J, Lin CP. Extensive Cortical Connectivity of the Human Hippocampal Memory System: Beyond the "What" and "Where" Dual Stream Model. Cerebral Cortex. 2021 May 19;bhab113. doi: 10.1093/cercor/bhab113.
- Lin HY#, Huang CC#*, Chou KH, Yang AC, Lo CZ, Tsai SJ, Lin CP. Differential Patterns of Gyral and Sulcal Morphological Changes During Normal Aging Process. Front Aging Neurosci. 2021 Feb. 2021;13:625931.
- Huang CC#, Luo Q #, Palaniyappan L#, Yang AC, Hung CC, Chou KH, Lo CY, Liu MN, Tsai SJ, Barch DM, Feng J*, Lin CP*, Robbins TW. Transdiagnostic and Illness-specific Functional Dysconnectivity Across Schizophrenia, Bipolar Disorder and Major Depression. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. 2020 Feb 10. https://doi.org/10.1016/j.bpsc.2020.01.010.
- Rolls ET#*, Huang CC#, Lin CP, Feng J, Joliot M. Automated anatomical labelling atlas 3. Neuroimage. 2020 Feb 1;206:116189. Epub 2019 Sep 12.
- Huang CC, Yang AC, Chou KH, Liu ME, Fang SC, Chen CC, Tsai SJ, Lin CP. (2018, Mar). Nonlinear pattern of the emergence of white matter hyperintensity in healthy Han Chinese: an adult lifespan study. Neurobiology of Aging, Jul;67:99-107.
- Huang CC, Liu ME, Chou KH, Yang AC, Hung CC, Hong CJ, Tsai SJ, Lin CP. (2014, Jan). Effect of BDNF Val66Met polymorphism on regional white matter hyperintensities and cognitive function in elderly males without dementia. Psychoneuroendocrinology, 39:94-103.